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Azathioprine

Generic alternative to Imuran

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Azathioprine is an immunosuppressive medication used primarily in the management of autoimmune diseases and in preventing transplant rejection. It works by inhibiting the synthesis of DNA in immune cells, thereby reducing their proliferation and activity.

How is this medication used?

Azathioprine is taken orally with or without food, usually once or twice daily according to the prescription provided by a healthcare provider. Dosage is based on medical condition, response to treatment, and, in the case of transplant patients, the type of transplant and concomitant medication.

What are the possible side effects?

Common side effects include increased susceptibility to infections, nausea, vomiting, diarrhea, and decreased blood counts including anemia, leukopenia, and thrombocytopenia. Long-term use can increase the risk of developing lymphoma and other malignancies, liver damage, and pancreatitis.

What are the potential interactions?

Azathioprine can interact with allopurinol, febuxostat, warfarin, aminosalicylates (such as mesalamine, olsalazine, and sulfasalazine), and vaccines. The combination with allopurinol or febuxostat requires special attention as it can significantly increase azathioprine's toxicity.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.

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